Nouvel article accepté dans la revue "Reports of Practical Oncology and Radiotherapy"

Biological effects and equivalent doses in radiotherapy: a software solution

Cyril Voyant, Daniel Julian, Rudy Roustit, Katia Biffi, Céline Lantieri


Nouvel article accepté dans la revue "Reports of Practical Oncology and Radiotherapy"
Cet article expose les différents modèles utilisés dans le logiciel de calcul d'équivalent de dose LQ-equiv. Outre l'aspect purement scientifique, une étude comparative des différents modes de calcul utilisés dans certain service de radiothérapie français est discutée. Le résumé de cette publication est :

" The limits of TDF (time, dose, and fractionation) and linear quadratic models have been known for a long time. Medical physicists and physicians are required to provide fast and reliable interpretations regarding the delivered doses or any future prescriptions relating to treatment changes. We therefore propose a calculation interface under the GNU license to be used for equivalent doses, biological doses, and normal tumor complication probability (Lyman model). The methodology used draws from several sources: the linear-quadratic-linear model of Astrahan, the repopulation effects of Dale, and the prediction of multi-fractionated treatments of Thames. The results are obtained from an algorithm that minimizes an ad-hoc cost function, and then compared to the equivalent dose computed using standard calculators in seven French radiotherapy centers."

lq_equiv.pdf Lq-equiv.pdf  (815.12 Ko)



Rédigé par Cyril VOYANT le Jeudi 22 Août 2013 à 20:27 | Lu 506 fois